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Development and validation of an HPLC method to determine the stability of fentanyl citrate and bupivacaine hydrochloride mixtures in infusion solutions

BACKGROUND: The use of a combination of different drugs in postoperative analgesia extends the time of analgesia, makes it more efficient and allows the use of lower drug doses, which leads to less risk of side effects and drug dependence. The aim of this study was to develop and validate an HPLC me...

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Detalles Bibliográficos
Autores principales: Piekarski, Mikołaj, Jelin'ska, Anna, Szymczak, Kamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591257/
https://www.ncbi.nlm.nih.gov/pubmed/23487596
http://dx.doi.org/10.1136/ejhpharm-2012-000088