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Interpretation of Genomic Variants Using a Unified Biological Network Approach

The decreasing cost of sequencing is leading to a growing repertoire of personal genomes. However, we are lagging behind in understanding the functional consequences of the millions of variants obtained from sequencing. Global system-wide effects of variants in coding genes are particularly poorly u...

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Detalles Bibliográficos
Autores principales: Khurana, Ekta, Fu, Yao, Chen, Jieming, Gerstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591262/
https://www.ncbi.nlm.nih.gov/pubmed/23505346
http://dx.doi.org/10.1371/journal.pcbi.1002886