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Interpretation of Genomic Variants Using a Unified Biological Network Approach
The decreasing cost of sequencing is leading to a growing repertoire of personal genomes. However, we are lagging behind in understanding the functional consequences of the millions of variants obtained from sequencing. Global system-wide effects of variants in coding genes are particularly poorly u...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591262/ https://www.ncbi.nlm.nih.gov/pubmed/23505346 http://dx.doi.org/10.1371/journal.pcbi.1002886 |