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Comparative RNA-seq Analysis in the Unsequenced Axolotl: The Oncogene Burst Highlights Early Gene Expression in the Blastema

The salamander has the remarkable ability to regenerate its limb after amputation. Cells at the site of amputation form a blastema and then proliferate and differentiate to regrow the limb. To better understand this process, we performed deep RNA sequencing of the blastema over a time course in the...

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Detalles Bibliográficos
Autores principales: Stewart, Ron, Rascón, Cynthia Alexander, Tian, Shulan, Nie, Jeff, Barry, Chris, Chu, Li-Fang, Ardalani, Hamisha, Wagner, Ryan J., Probasco, Mitchell D., Bolin, Jennifer M., Leng, Ning, Sengupta, Srikumar, Volkmer, Michael, Habermann, Bianca, Tanaka, Elly M., Thomson, James A., Dewey, Colin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591270/
https://www.ncbi.nlm.nih.gov/pubmed/23505351
http://dx.doi.org/10.1371/journal.pcbi.1002936