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RFX Transcription Factor DAF-19 Regulates 5-HT and Innate Immune Responses to Pathogenic Bacteria in Caenorhabditis elegans

In Caenorhabditis elegans the Toll-interleukin receptor domain adaptor protein TIR-1 via a conserved mitogen-activated protein kinase (MAPK) signaling cascade induces innate immunity and upregulates serotonin (5-HT) biosynthesis gene tph-1 in a pair of ADF chemosensory neurons in response to infecti...

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Detalles Bibliográficos
Autores principales: Xie, Yusu, Moussaif, Mustapha, Choi, Sunju, Xu, Lu, Sze, Ji Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591283/
https://www.ncbi.nlm.nih.gov/pubmed/23505381
http://dx.doi.org/10.1371/journal.pgen.1003324