A Natural Polymorphism in rDNA Replication Origins Links Origin Activation with Calorie Restriction and Lifespan

Aging and longevity are complex traits influenced by genetic and environmental factors. To identify quantitative trait loci (QTLs) that control replicative lifespan, we employed an outbred Saccharomyces cerevisiae model, generated by crossing a vineyard and a laboratory strain. The predominant QTL m...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwan, Elizabeth X., Foss, Eric J., Tsuchiyama, Scott, Alvino, Gina M., Kruglyak, Leonid, Kaeberlein, Matt, Raghuraman, M. K., Brewer, Bonita J., Kennedy, Brian K., Bedalov, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591295/
https://www.ncbi.nlm.nih.gov/pubmed/23505383
http://dx.doi.org/10.1371/journal.pgen.1003329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591295/
https://www.ncbi.nlm.nih.gov/pubmed/23505383
http://dx.doi.org/10.1371/journal.pgen.1003329

Ejemplares similares