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Positively Selected Sites in Cetacean Myoglobins Contribute to Protein Stability
Since divergence ∼50 Ma ago from their terrestrial ancestors, cetaceans underwent a series of adaptations such as a ∼10–20 fold increase in myoglobin (Mb) concentration in skeletal muscle, critical for increasing oxygen storage capacity and prolonging dive time. Whereas the O(2)-binding affinity of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591298/ https://www.ncbi.nlm.nih.gov/pubmed/23505347 http://dx.doi.org/10.1371/journal.pcbi.1002929 |