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A Role for the Malignant Brain Tumour (MBT) Domain Protein LIN-61 in DNA Double-Strand Break Repair by Homologous Recombination

Malignant brain tumour (MBT) domain proteins are transcriptional repressors that function within Polycomb complexes. Some MBT genes are tumour suppressors, but how they prevent tumourigenesis is unknown. The Caenorhabditis elegans MBT protein LIN-61 is a member of the synMuvB chromatin-remodelling p...

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Detalles Bibliográficos
Autores principales: Johnson, Nicholas M., Lemmens, Bennie B. L. G., Tijsterman, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591299/
https://www.ncbi.nlm.nih.gov/pubmed/23505385
http://dx.doi.org/10.1371/journal.pgen.1003339