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Fates of Retroviral Core Components during Unrestricted and TRIM5-Restricted Infection

TRIM5 proteins can restrict retroviral infection soon after delivery of the viral core into the cytoplasm. However, the molecular mechanisms by which TRIM5α inhibits infection have been elusive, in part due to the difficulty of developing and executing biochemical assays that examine this stage of t...

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Detalles Bibliográficos
Autores principales: Kutluay, Sebla B., Perez-Caballero, David, Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591316/
https://www.ncbi.nlm.nih.gov/pubmed/23505372
http://dx.doi.org/10.1371/journal.ppat.1003214