Decreased IL-7 Responsiveness Is Related to Oxidative Stress in HIV Disease

HIV disease results in decreased IL-7 receptor expression and IL-7 responsiveness in T cells. To explore mechanisms of these deficiencies, we compared CD127 expression and IL-7 induction of P-STAT5 in T cells from HIV-infected persons with serum concentrations of cytokines (IL-7, IL-6 and IL-15), ma...

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Detalles Bibliográficos
Autores principales: Kalinowska, Magdalina, Bazdar, Douglas A., Lederman, Michael M., Funderburg, Nicholas, Sieg, Scott F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591367/
https://www.ncbi.nlm.nih.gov/pubmed/23505558
http://dx.doi.org/10.1371/journal.pone.0058764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591367/
https://www.ncbi.nlm.nih.gov/pubmed/23505558
http://dx.doi.org/10.1371/journal.pone.0058764

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