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Decreased IL-7 Responsiveness Is Related to Oxidative Stress in HIV Disease
HIV disease results in decreased IL-7 receptor expression and IL-7 responsiveness in T cells. To explore mechanisms of these deficiencies, we compared CD127 expression and IL-7 induction of P-STAT5 in T cells from HIV-infected persons with serum concentrations of cytokines (IL-7, IL-6 and IL-15), ma...
Autores principales: | Kalinowska, Magdalina, Bazdar, Douglas A., Lederman, Michael M., Funderburg, Nicholas, Sieg, Scott F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591367/ https://www.ncbi.nlm.nih.gov/pubmed/23505558 http://dx.doi.org/10.1371/journal.pone.0058764 |
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