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Human Mas-Related G Protein-Coupled Receptors-X1 Induce Chemokine Receptor 2 Expression in Rat Dorsal Root Ganglia Neurons and Release of Chemokine Ligand 2 from the Human LAD-2 Mast Cell Line

Primate-specific Mas-related G protein-coupled receptors-X1 (MRGPR-X1) are highly enriched in dorsal root ganglia (DRG) neurons and induce acute pain. Herein, we analyzed effects of MRGPR-X1 on serum response factors (SRF) or nuclear factors of activated T cells (NFAT), which control expression of v...

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Detalles Bibliográficos
Autores principales: Solinski, Hans Jürgen, Petermann, Franziska, Rothe, Kathrin, Boekhoff, Ingrid, Gudermann, Thomas, Breit, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591377/
https://www.ncbi.nlm.nih.gov/pubmed/23505557
http://dx.doi.org/10.1371/journal.pone.0058756