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Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase
Soluble guanylate cyclase (sGC) catalyses the synthesis of cyclic GMP in response to nitric oxide. The enzyme is a heterodimer of homologous α and β subunits, each of which is composed of multiple domains. We present here crystal structures of a heterodimer of the catalytic domains of the α and β su...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591389/ https://www.ncbi.nlm.nih.gov/pubmed/23505436 http://dx.doi.org/10.1371/journal.pone.0057644 |