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Long-Term Post-Stroke Changes Include Myelin Loss, Specific Deficits in Sensory and Motor Behaviors and Complex Cognitive Impairment Detected Using Active Place Avoidance

Persistent neurobehavioral deficits and brain changes need validation for brain restoration. Two hours middle cerebral artery occlusion (tMCAO) or sham surgery was performed in male Sprague-Dawley rats. Neurobehavioral and cognitive deficits were measured over 10 weeks included: (1) sensory, motor,...

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Detalles Bibliográficos
Autores principales: Zhou, Jin, Zhuang, Jian, Li, Jie, Ooi, Evelyn, Bloom, Jonathan, Poon, Carrie, Lax, Daniel, Rosenbaum, Daniel M., Barone, Frank C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591420/
https://www.ncbi.nlm.nih.gov/pubmed/23505432
http://dx.doi.org/10.1371/journal.pone.0057503