Characterization of Nasal Potential Difference in cftr Knockout and F508del-CFTR Mice

BACKGROUND: Treatments designed to correct cystic fibrosis transmembrane conductance regulator (CFTR) defects must first be evaluated in preclinical experiments in the mouse model of cystic fibrosis (CF). Mice nasal mucosa mimics the bioelectric defect seen in humans. The use of nasal potential diff...

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Detalles Bibliográficos
Autores principales: Saussereau, Emilie Lyne, Roussel, Delphine, Diallo, Siradiou, Debarbieux, Laurent, Edelman, Aleksander, Sermet-Gaudelus, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591431/
https://www.ncbi.nlm.nih.gov/pubmed/23505426
http://dx.doi.org/10.1371/journal.pone.0057317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591431/
https://www.ncbi.nlm.nih.gov/pubmed/23505426
http://dx.doi.org/10.1371/journal.pone.0057317

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