Ablation of BRaf Impairs Neuronal Differentiation in the Postnatal Hippocampus and Cerebellum

This study focuses on the role of the kinase BRaf in postnatal brain development. Mice expressing truncated, non-functional BRaf in neural stem cell-derived brain tissue demonstrate alterations in the cerebellum, with decreased sizes and fuzzy borders of the glomeruli in the granule cell layer. In a...

Descripción completa

Detalles Bibliográficos
Autores principales: Pfeiffer, Verena, Götz, Rudolf, Xiang, Chaomei, Camarero, Guadelupe, Braun, Attila, Zhang, Yina, Blum, Robert, Heinsen, Helmut, Nieswandt, Bernhard, Rapp, Ulf R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591433/
https://www.ncbi.nlm.nih.gov/pubmed/23505473
http://dx.doi.org/10.1371/journal.pone.0058259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591433/
https://www.ncbi.nlm.nih.gov/pubmed/23505473
http://dx.doi.org/10.1371/journal.pone.0058259

Ejemplares similares