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Ablation of BRaf Impairs Neuronal Differentiation in the Postnatal Hippocampus and Cerebellum

This study focuses on the role of the kinase BRaf in postnatal brain development. Mice expressing truncated, non-functional BRaf in neural stem cell-derived brain tissue demonstrate alterations in the cerebellum, with decreased sizes and fuzzy borders of the glomeruli in the granule cell layer. In a...

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Detalles Bibliográficos
Autores principales:	Pfeiffer, Verena, Götz, Rudolf, Xiang, Chaomei, Camarero, Guadelupe, Braun, Attila, Zhang, Yina, Blum, Robert, Heinsen, Helmut, Nieswandt, Bernhard, Rapp, Ulf R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591433/ https://www.ncbi.nlm.nih.gov/pubmed/23505473 http://dx.doi.org/10.1371/journal.pone.0058259

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