Pyrimidine Biosynthesis Is Not an Essential Function for Trypanosoma brucei Bloodstream Forms

BACKGROUND: African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host, but it is unknown whether either process is essential to the parasite. METHODOLOGY/PRINCIPAL FINDINGS: Pyrimidine requirements for growth were investigated using strictly...

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Detalles Bibliográficos
Autores principales: Ali, Juma A. M., Tagoe, Daniel N. A., Munday, Jane C., Donachie, Anne, Morrison, Liam J., de Koning, Harry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591441/
https://www.ncbi.nlm.nih.gov/pubmed/23505454
http://dx.doi.org/10.1371/journal.pone.0058034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591441/
https://www.ncbi.nlm.nih.gov/pubmed/23505454
http://dx.doi.org/10.1371/journal.pone.0058034

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