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Pyrimidine Biosynthesis Is Not an Essential Function for Trypanosoma brucei Bloodstream Forms

BACKGROUND: African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host, but it is unknown whether either process is essential to the parasite. METHODOLOGY/PRINCIPAL FINDINGS: Pyrimidine requirements for growth were investigated using strictly...

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Detalles Bibliográficos
Autores principales:	Ali, Juma A. M., Tagoe, Daniel N. A., Munday, Jane C., Donachie, Anne, Morrison, Liam J., de Koning, Harry P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591441/ https://www.ncbi.nlm.nih.gov/pubmed/23505454 http://dx.doi.org/10.1371/journal.pone.0058034

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