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Biodistribution and Elimination Study of Fluorine-18 Labeled N(ε)-Carboxymethyl-Lysine following Intragastric and Intravenous Administration

BACKGROUND: N(ε)-carboxymethyl-lysine (CML) is a major advanced glycation end-product (AGEs) widely found in foods. The aim of our study was to evaluate how exogenous CML-peptide is dynamically absorbed from the gastrointestinal tract and eliminated by renal tubular secretion using microPET imaging....

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Detalles Bibliográficos
Autores principales: Xu, Hongzeng, Wang, Zhongqun, Wang, Yan, Hu, Shengda, Liu, Naifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591457/
https://www.ncbi.nlm.nih.gov/pubmed/23505446
http://dx.doi.org/10.1371/journal.pone.0057897