Naïve pluripotency is associated with global DNA hypomethylation

Naïve pluripotent embryonic stem (ESCs) cells and embryonic germ (EGCs) cells are derived from the preimplantation epiblast and primordial germ cells (PGCs), respectively. We investigated whether differences exist between ESCs and EGCs in view of their distinct developmental origins. PGCs are progra...

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Detalles Bibliográficos
Autores principales: Leitch, Harry G., McEwen, Kirsten R., Turp, Aleksandra, Encheva, Vesela, Carroll, Tom, Grabole, Nils, Mansfield, William, Nashun, Buhe, Knezovich, Jaysen G., Smith, Austin, Surani, M. Azim, Hajkova, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591483/
https://www.ncbi.nlm.nih.gov/pubmed/23416945
http://dx.doi.org/10.1038/nsmb.2510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591483/
https://www.ncbi.nlm.nih.gov/pubmed/23416945
http://dx.doi.org/10.1038/nsmb.2510

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