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Mitochondrial permeability transition pore as a selective target for anti-cancer therapy

Mitochondrial outer membrane permeabilization (MOMP) is the ultimate step in dozens of lethal apoptotic signal transduction pathways which converge on mitochondria. One of the representative systems proposed to be responsible for the MOMP is the mitochondrial permeability transition pore (MPTP). Alt...

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Detalles Bibliográficos
Autores principales: Suh, Dong H., Kim, Mi-Kyung, Kim, Hee S., Chung, Hyun H., Song, Yong S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592197/
https://www.ncbi.nlm.nih.gov/pubmed/23483560
http://dx.doi.org/10.3389/fonc.2013.00041