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Cross-talk between prion protein and quadruplex-forming nucleic acids: a dynamic complex formation

Prion protein (PrP) is involved in lethal neurodegenerative diseases, and many issues remain unclear about its physio-pathological role. Quadruplex-forming nucleic acids (NAs) have been found to specifically bind to both PrP cellular and pathological isoforms. To clarify the relevance of these inter...

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Detalles Bibliográficos
Autores principales: Cavaliere, Paola, Pagano, Bruno, Granata, Vincenzo, Prigent, Stephanie, Rezaei, Human, Giancola, Concetta, Zagari, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592392/
https://www.ncbi.nlm.nih.gov/pubmed/23104426
http://dx.doi.org/10.1093/nar/gks970