Sensitive measurement of single-nucleotide polymorphism-induced changes of RNA conformation: application to disease studies

Single-nucleotide polymorphisms (SNPs) are often linked to critical phenotypes such as diseases or responses to vaccines, medications and environmental factors. However, the specific molecular mechanisms by which a causal SNP acts is usually not obvious. Changes in RNA secondary structure emerge as...

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Detalles Bibliográficos
Autores principales: Salari, Raheleh, Kimchi-Sarfaty, Chava, Gottesman, Michael M., Przytycka, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592397/
https://www.ncbi.nlm.nih.gov/pubmed/23125360
http://dx.doi.org/10.1093/nar/gks1009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592397/
https://www.ncbi.nlm.nih.gov/pubmed/23125360
http://dx.doi.org/10.1093/nar/gks1009

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