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Sensitive measurement of single-nucleotide polymorphism-induced changes of RNA conformation: application to disease studies
Single-nucleotide polymorphisms (SNPs) are often linked to critical phenotypes such as diseases or responses to vaccines, medications and environmental factors. However, the specific molecular mechanisms by which a causal SNP acts is usually not obvious. Changes in RNA secondary structure emerge as...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592397/ https://www.ncbi.nlm.nih.gov/pubmed/23125360 http://dx.doi.org/10.1093/nar/gks1009 |