Structural asymmetry in the Thermus thermophilus RuvC dimer suggests a basis for sequential strand cleavages during Holliday junction resolution

Holliday junction (HJ) resolvases are structure-specific endonucleases that cleave four-way DNA junctions (HJs) generated during DNA recombination and repair. Bacterial RuvC, a prototypical HJ resolvase, functions as homodimer and nicks DNA strands precisely across the junction point. To gain insigh...

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Detalles Bibliográficos
Autores principales: Chen, Luan, Shi, Ke, Yin, Zhiqi, Aihara, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592405/
https://www.ncbi.nlm.nih.gov/pubmed/23118486
http://dx.doi.org/10.1093/nar/gks1015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592405/
https://www.ncbi.nlm.nih.gov/pubmed/23118486
http://dx.doi.org/10.1093/nar/gks1015

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