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Analysis of RNA cleavage by MALDI-TOF mass spectrometry

A method of analysis is presented that utilizes matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) to monitor the kinetics and products of RNA cleavage, by use of a program designed to mass-match observed MS peaks with predicted RNA cleavage products. The met...

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Detalles Bibliográficos
Autores principales: Joyner, Jeff C., Keuper, Kevin D., Cowan, J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592410/
https://www.ncbi.nlm.nih.gov/pubmed/22941655
http://dx.doi.org/10.1093/nar/gks811