Natural zinc ribbon HNH endonucleases and engineered zinc finger nicking endonuclease

Many bacteriophage and prophage genomes encode an HNH endonuclease (HNHE) next to their cohesive end site and terminase genes. The HNH catalytic domain contains the conserved catalytic residues His-Asn-His and a zinc-binding site [CxxC](2). An additional zinc ribbon (ZR) domain with one to two zinc-...

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Detalles Bibliográficos
Autores principales: Xu, Shuang-yong, Gupta, Yogesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592412/
https://www.ncbi.nlm.nih.gov/pubmed/23125367
http://dx.doi.org/10.1093/nar/gks1043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592412/
https://www.ncbi.nlm.nih.gov/pubmed/23125367
http://dx.doi.org/10.1093/nar/gks1043

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