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Natural zinc ribbon HNH endonucleases and engineered zinc finger nicking endonuclease
Many bacteriophage and prophage genomes encode an HNH endonuclease (HNHE) next to their cohesive end site and terminase genes. The HNH catalytic domain contains the conserved catalytic residues His-Asn-His and a zinc-binding site [CxxC](2). An additional zinc ribbon (ZR) domain with one to two zinc-...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592412/ https://www.ncbi.nlm.nih.gov/pubmed/23125367 http://dx.doi.org/10.1093/nar/gks1043 |