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miRNA repression of translation in vitro takes place during 43S ribosomal scanning

microRNAs (miRNAs) regulate gene expression at multiple levels by repressing translation, stimulating deadenylation and inducing the premature decay of target messenger RNAs (mRNAs). Although the mechanism by which miRNAs repress translation has been widely studied, the precise step targeted and the...

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Detalles Bibliográficos
Autores principales: Ricci, Emiliano P., Limousin, Taran, Soto-Rifo, Ricardo, Rubilar, Paulina S., Decimo, Didier, Ohlmann, Théophile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592420/
https://www.ncbi.nlm.nih.gov/pubmed/23161679
http://dx.doi.org/10.1093/nar/gks1076