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The RNA-binding domain of influenzavirus non-structural protein-1 cooperatively binds to virus-specific RNA sequences in a structure-dependent manner

Influenzavirus non-structural protein NS1 is involved in several steps of the virus replication cycle. It counteracts the interferon response, and also exhibits other activities towards viral and cellular RNAs. NS1 is known to bind non-specifically to double-stranded RNA (dsRNA) as well as to viral...

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Detalles Bibliográficos
Autores principales: Marc, Daniel, Barbachou, Sosthène, Soubieux, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592425/
https://www.ncbi.nlm.nih.gov/pubmed/23093596
http://dx.doi.org/10.1093/nar/gks979