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FadE: whole genome methylation analysis for multiple sequencing platforms

DNA methylation plays a central role in genomic regulation and disease. Sodium bisulfite treatment (SBT) causes unmethylated cytosines to be sequenced as thymine, which allows methylation levels to reflected in the number of ‘C’-‘C’ alignments covering reference cytosines. Di-base color reads produc...

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Detalles Bibliográficos
Autores principales: Souaiaia, Tade, Zhang, Zheng, Chen, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592442/
https://www.ncbi.nlm.nih.gov/pubmed/22965123
http://dx.doi.org/10.1093/nar/gks830