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FadE: whole genome methylation analysis for multiple sequencing platforms
DNA methylation plays a central role in genomic regulation and disease. Sodium bisulfite treatment (SBT) causes unmethylated cytosines to be sequenced as thymine, which allows methylation levels to reflected in the number of ‘C’-‘C’ alignments covering reference cytosines. Di-base color reads produc...
Autores principales: | Souaiaia, Tade, Zhang, Zheng, Chen, Ting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592442/ https://www.ncbi.nlm.nih.gov/pubmed/22965123 http://dx.doi.org/10.1093/nar/gks830 |
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