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DNA expansions generated by human Polµ on iterative sequences

Polµ is the only DNA polymerase equipped with template-directed and terminal transferase activities. Polµ is also able to accept distortions in both primer and template strands, resulting in misinsertions and extension of realigned mismatched primer terminus. In this study, we propose a model for hu...

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Detalles Bibliográficos
Autores principales: Aza, Ana, Martin, Maria Jose, Juarez, Raquel, Blanco, Luis, Terrados, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592450/
https://www.ncbi.nlm.nih.gov/pubmed/23143108
http://dx.doi.org/10.1093/nar/gks1054