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Contribution of intersubunit bridges to the energy barrier of ribosomal translocation

In every round of translation elongation, EF-G catalyzes translocation, the movement of tRNAs (and paired codons) to their adjacent binding sites in the ribosome. Previous kinetic studies have shown that the rate of tRNA–mRNA movement is limited by a conformational change in the ribosome termed ‘unl...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Fredrick, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592451/
https://www.ncbi.nlm.nih.gov/pubmed/23161696
http://dx.doi.org/10.1093/nar/gks1074