Quaternary structure of the yeast Arc1p-aminoacyl-tRNA synthetase complex in solution and its compaction upon binding of tRNAs

In the yeast Saccharomyces cerevisiae, the aminoacyl-tRNA synthetases (aaRS) GluRS and MetRS form a complex with the auxiliary protein cofactor Arc1p. The latter binds the N-terminal domains of both synthetases increasing their affinity for the transfer-RNA (tRNA) substrates tRNA(Met) and tRNA(Glu)....

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Detalles Bibliográficos
Autores principales: Koehler, Christine, Round, Adam, Simader, Hannes, Suck, Dietrich, Svergun, Dmitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592460/
https://www.ncbi.nlm.nih.gov/pubmed/23161686
http://dx.doi.org/10.1093/nar/gks1072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592460/
https://www.ncbi.nlm.nih.gov/pubmed/23161686
http://dx.doi.org/10.1093/nar/gks1072

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