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Translational fidelity maintenance preventing Ser mis-incorporation at Thr codon in protein from eukaryote

Aminoacyl-tRNA synthetase (aaRS) catalyzes the first step of protein synthesis, producing aminoacyl-tRNAs as building blocks. Eukaryotic aaRS differs from its prokaryotic counterpart in terminal extension or insertion. Moreover, the editing function of aaRSs is an indispensable checkpoint excluding...

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Detalles Bibliográficos
Autores principales: Zhou, Xiao-Long, Ruan, Zhi-Rong, Huang, Qian, Tan, Min, Wang, En-Duo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592468/
https://www.ncbi.nlm.nih.gov/pubmed/23093606
http://dx.doi.org/10.1093/nar/gks982