Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization

Progression to malignancy requires that cells overcome senescence and switch to an immortal phenotype. Thus, exploring the genetic and epigenetic changes that occur during senescence/immortalization may help elucidate crucial events that lead to cell transformation. In the present study, we have glo...

Descripción completa

Detalles Bibliográficos
Autores principales: Tommasi, Stella, Zheng, Albert, Weninger, Annette, Bates, Steven E., Li, Xuejun Arthur, Wu, Xiwei, Hollstein, Monica, Besaratinia, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592471/
https://www.ncbi.nlm.nih.gov/pubmed/23143272
http://dx.doi.org/10.1093/nar/gks1051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592471/
https://www.ncbi.nlm.nih.gov/pubmed/23143272
http://dx.doi.org/10.1093/nar/gks1051

Ejemplares similares