Cargando…
Identification of one of the apurinic/apyrimidinic lyase active sites of topoisomerase V by structural and functional studies
Topoisomerase V (Topo-V) is the only member of a novel topoisomerase subtype. Topo-V is unique because it is a bifunctional enzyme carrying both topoisomerase and DNA repair lyase activities within the same protein. Previous studies had shown that the topoisomerase domain spans the N-terminus of the...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592480/ https://www.ncbi.nlm.nih.gov/pubmed/23125368 http://dx.doi.org/10.1093/nar/gks1017 |