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Fluorescence-Based High-Throughput Functional Profiling of Ligand-Gated Ion Channels at the Level of Single Cells

Ion channels are involved in many physiological processes and are attractive targets for therapeutic intervention. Their functional properties vary according to their subunit composition, which in turn varies in a developmental and tissue-specific manner and as a consequence of pathophysiological ev...

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Detalles Bibliográficos
Autores principales: Talwar, Sahil, Lynch, Joseph W., Gilbert, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592791/
https://www.ncbi.nlm.nih.gov/pubmed/23520514
http://dx.doi.org/10.1371/journal.pone.0058479