Recombinant Vectors Based on Porcine Adeno-Associated Viral Serotypes Transduce the Murine and Pig Retina

Recombinant adeno-associated viral (AAV) vectors are known to safely and efficiently transduce the retina. Among the various AAV serotypes available, AAV2/5 and 2/8 are the most effective for gene transfer to photoreceptors (PR), which are the most relevant targets for gene therapy of inherited reti...

Descripción completa

Detalles Bibliográficos
Autores principales: Puppo, Agostina, Bello, Alexander, Manfredi, Anna, Cesi, Giulia, Marrocco, Elena, Corte, Michele Della, Rossi, Settimio, Giunti, Massimo, Bacci, Maria Laura, Simonelli, Francesca, Surace, Enrico Maria, Kobinger, Gary P., Auricchio, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592811/
https://www.ncbi.nlm.nih.gov/pubmed/23520549
http://dx.doi.org/10.1371/journal.pone.0059025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592811/
https://www.ncbi.nlm.nih.gov/pubmed/23520549
http://dx.doi.org/10.1371/journal.pone.0059025

Ejemplares similares