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Oleuropein Aglycone Protects Transgenic C. elegans Strains Expressing Aβ42 by Reducing Plaque Load and Motor Deficit

The presence of amyloid aggregates of the 42 amino acid peptide of amyloid beta (Aβ42) in the brain is the characteristic feature of Alzheimer’s disease (AD). Amyloid beta (Aβ deposition is also found in muscle fibers of individuals affected by inclusion body myositis (sIBM), a rare muscular degener...

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Detalles Bibliográficos
Autores principales: Diomede, Luisa, Rigacci, Stefania, Romeo, Margherita, Stefani, Massimo, Salmona, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592812/
https://www.ncbi.nlm.nih.gov/pubmed/23520540
http://dx.doi.org/10.1371/journal.pone.0058893