Phospholipid Metabolites in Recurrent Glioblastoma: In Vivo Markers Detect Different Tumor Phenotypes before and under Antiangiogenic Therapy

PURPOSE: Metabolic changes upon antiangiogenic therapy of recurrent glioblastomas (rGBMs) may provide new biomarkers for treatment efficacy. Since in vitro models showed that phospholipid membrane metabolism provides specific information on tumor growth we employed in-vivo MR-spectroscopic imaging (...

Descripción completa

Detalles Bibliográficos
Autores principales: Hattingen, Elke, Bähr, Oliver, Rieger, Johannes, Blasel, Stella, Steinbach, Joachim, Pilatus, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592858/
https://www.ncbi.nlm.nih.gov/pubmed/23520454
http://dx.doi.org/10.1371/journal.pone.0056439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592858/
https://www.ncbi.nlm.nih.gov/pubmed/23520454
http://dx.doi.org/10.1371/journal.pone.0056439

Ejemplares similares