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Protein Phosphorylation Profiling Using an In Situ Proximity Ligation Assay: Phosphorylation of AURKA-Elicited EGFR-Thr654 and EGFR-Ser1046 in Lung Cancer Cells

The epidermal growth factor receptor (EGFR), which is up-regulated in lung cancer, involves the activation of mitogenic signals and triggers multiple signaling cascades. To dissect these EGFR cascades, we used 14 different phospho-EGFR antibodies to quantify protein phosphorylation using an in situ...

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Detalles Bibliográficos
Autores principales: Chen, Tzu-Chi, Liu, Yu-Wen, Huang, Yei-Hsuan, Yeh, Yi-Chen, Chou, Teh-Ying, Wu, Yu-Chung, Wu, Chun-Chi, Chen, Yi-Rong, Cheng, Hui-Chuan, Lu, Pei-Jung, Lai, Jin-Mei, Huang, Chi-Ying F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592865/
https://www.ncbi.nlm.nih.gov/pubmed/23520446
http://dx.doi.org/10.1371/journal.pone.0055657