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Detection of Drug-Drug Interactions by Modeling Interaction Profile Fingerprints

Drug-drug interactions (DDIs) constitute an important problem in postmarketing pharmacovigilance and in the development of new drugs. The effectiveness or toxicity of a medication could be affected by the co-administration of other drugs that share pharmacokinetic or pharmacodynamic pathways. For th...

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Detalles Bibliográficos
Autores principales: Vilar, Santiago, Uriarte, Eugenio, Santana, Lourdes, Tatonetti, Nicholas P., Friedman, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592896/
https://www.ncbi.nlm.nih.gov/pubmed/23520498
http://dx.doi.org/10.1371/journal.pone.0058321