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Detection of Drug-Drug Interactions by Modeling Interaction Profile Fingerprints
Drug-drug interactions (DDIs) constitute an important problem in postmarketing pharmacovigilance and in the development of new drugs. The effectiveness or toxicity of a medication could be affected by the co-administration of other drugs that share pharmacokinetic or pharmacodynamic pathways. For th...
Autores principales: | Vilar, Santiago, Uriarte, Eugenio, Santana, Lourdes, Tatonetti, Nicholas P., Friedman, Carol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592896/ https://www.ncbi.nlm.nih.gov/pubmed/23520498 http://dx.doi.org/10.1371/journal.pone.0058321 |
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