On how mammalian transcription factors recognize methylated DNA

DNA methylation is an epigenetic mark that is essential for the development of mammals; it is frequently altered in diseases ranging from cancer to psychiatric disorders. The presence of DNA methylation attracts specialized methyl-DNA binding factors that can then recruit chromatin modifiers. These...

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Detalles Bibliográficos
Autores principales: Buck-Koehntop, Bethany A., Defossez, Pierre-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Point of View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592898/
https://www.ncbi.nlm.nih.gov/pubmed/23324617
http://dx.doi.org/10.4161/epi.23632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592898/
https://www.ncbi.nlm.nih.gov/pubmed/23324617
http://dx.doi.org/10.4161/epi.23632

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