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Human metastable epiallele candidates link to common disorders

Metastable epialleles (MEs) are mammalian genomic loci where epigenetic patterning occurs before gastrulation in a stochastic fashion leading to systematic interindividual variation within one species. Importantly, periconceptual nutritional influences may modulate the establishment of epigenetic ch...

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Detalles Bibliográficos
Autores principales: Harris, R. Alan, Nagy-Szakal, Dorottya, Kellermayer, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592901/
https://www.ncbi.nlm.nih.gov/pubmed/23321599
http://dx.doi.org/10.4161/epi.23438