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Chromosome X loci and spontaneous granulosa cell tumor development in SWR mice: Epigenetics and epistasis at work for an ovarian phenotype
Females of the SWR/Bm (SWR) inbred mouse strain possess a unique susceptibility to juvenile-onset tumors originating from the granulosa cells (GC) of the ovarian follicles. Tumor susceptibility is an inherited, polygenic trait in SWR females, minimally involving an oncogenic Granulosa cell tumor sus...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592904/ https://www.ncbi.nlm.nih.gov/pubmed/23299801 http://dx.doi.org/10.4161/epi.23399 |