Chromosome X loci and spontaneous granulosa cell tumor development in SWR mice: Epigenetics and epistasis at work for an ovarian phenotype

Females of the SWR/Bm (SWR) inbred mouse strain possess a unique susceptibility to juvenile-onset tumors originating from the granulosa cells (GC) of the ovarian follicles. Tumor susceptibility is an inherited, polygenic trait in SWR females, minimally involving an oncogenic Granulosa cell tumor sus...

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Detalles Bibliográficos
Autores principales: Dorward, Ann M., Yaskowiak, Edward S., Smith, Kerri N., Stanford, Kaitlyn R., Shultz, Kathryn L., Beamer, Wesley G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592904/
https://www.ncbi.nlm.nih.gov/pubmed/23299801
http://dx.doi.org/10.4161/epi.23399

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