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Pool-hmm: a Python program for estimating the allele frequency spectrum and detecting selective sweeps from next generation sequencing of pooled samples

Due to its cost effectiveness, next generation sequencing of pools of individuals (Pool-Seq) is becoming a popular strategy for genome-wide estimation of allele frequencies in population samples. As the allele frequency spectrum provides information about past episodes of selection, Pool-seq is also...

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Detalles Bibliográficos
Autores principales: Boitard, Simon, Kofler, Robert, Françoise, Pierre, Robelin, David, Schlötterer, Christian, Futschik, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592992/
https://www.ncbi.nlm.nih.gov/pubmed/23311589
http://dx.doi.org/10.1111/1755-0998.12063